Alyson Stoner

Little Engine (voice)

Whoopi Goldberg

The Tower (voice)

Patrick Warburton

The Caboose (voice)

Jeff Bennett

Hudson, Red Engine (voice)

Jodi Benson

Jillian (voice)

Corbin Bleu

Lou (voice)

Jim Cummings

Rusty (voice)

Jamie Lee Curtis

Beverly (voice)

Chelsea Evered

Girl Train (voice)

Khamani Griffin

Marcus (voice)

Dominic Scott Kay

Richard (voice)

Mocean Melvin

Big Locomotive (voice)

Suzy Nakamura

Teacher (voice)

Ray Porter

Nightmare Train (voice)

Michael S. Garcia

Scott (voice as Michael Rodrigo)

Rodney Saulsberry

Freight Train, Bud (voice)

Charlie Schlatter

Major (voice)

Brenda Song

Shiny Passenger Train (voice)