Rob Paulsen

Yakko Warner / Pinky / Dr. Otto Scratchansniff (voice)

Jess Harnell

Wakko Warner (voice)

Tress MacNeille

Dot Warner / Marita Hippo / Hello Nurse / Mindy's Mother (voice)

Maurice LaMarche

Brain / Squit (voice)

Nancy Cartwright

Mindy (voice)

Frank Welker

Various (voice)

Chick Vennera

Pesto (voice)

John Mariano

Bobby / Gas Station Attendant (voice)

Bernadette Peters

Rita (voice)

Sherri Stoner

Slappy Squirrel (voice)

Paxton Whitehead

King Salazar (voice)

Ben Stein

Desire Fulfillment Facilitator (voice)

Jeff Bennett

Captain of the Guard / Baloney (voice)

Paul Rugg

Mr. Director (voice)

Julie Brown

Minerva Mink (voice)

Tom Bodett

Narrator (voice)

Julie Bernstein

Singer (voice)

Steven Bernstein

Singer (voice)

Bobbi Page

Singer (voice)

Nathan Ruegger

Skippy Squirrel (voice)