Frank Welker

Fred Jones / Scooby-Doo (voice)

Mindy Cohn

Velma Dinkley (voice)

Matthew Lillard

Shaggy Rogers (voice)

Grey DeLisle

Daphne Blake (voice)

Gene Simmons

Demon (voice)

Paul Stanley

Starchild (voice)

Eric Singer

Catman (voice)

Garry Marshall

Manny Goldman (voice)

Doc McGhee

Chip McGhoo (voice)

Pauley Perrette

Delilah Domino (voice)

Rachel Ramras

Shandi Strutter (voice)

Penny Marshall

The Elder (voice)

Darius Rucker

The Destroyer (voice)

Jennifer Carpenter

Chikara (voice)

Jason Mewes

Worker #1 (voice)

Kevin Smith

Worker #2 (voice)

Tony Cervone

Announcer (voice)

Tommy Thayer

Spaceman (voice)