Frank Welker

Scooby-Doo / Fred Jones (voice)

Matthew Lillard

Shaggy Rogers (voice)

Grey DeLisle

Daphne Blake (voice)

Mindy Cohn

Velma Dinkley (voice)

Mark Hamill

Zip Elvin (voice)

Diedrich Bader

H.A.M. (voice)

Malcolm McDowell

Sly Baron (voice)

Fred Tatasciore

Hudson Baron / Alien (voice)

Jennifer Hale

Shannon Lucas / Ridley / Launch Manager (voice)

Jeff Bennett

Colt Steelcase (voice)

Kevin Michael Richardson

Uvinous "U-Boat" Botango / Drake (voice)

Eric Bauza

Clark Sporkman (voice)