Madonna

Self

Erika Belle

Dancer (segment "Lucky Star") (segment "Papa Don't Preach")

Christopher Ciccone

Dancer (segment "Lucky Star")

John Leguizamo

Friend of Boyfriend (segment "Borderline")

Louie Louie

Boyfriend (segment "Borderline")

Deke Anderson

The Director (segment "Material Girl")

Keith Carradine

Boyfriend (segment "Material Girl")

Sharon Oreck

Woman in clown costume (segment "Material Girl")

Robert Wuhl

Pitch Man (segment "Material Girl")

Danny Aiello

Papa (segment "Papa Don't Preach")

Debi Mazar

Friend (segment "Papa Don't Preach")

Alex McArthur

Boyfriend (segment "Papa Don't Preach")

Mailon Rivera

Friend (segment "Papa Don't Preach")

Felix Howard

Kid (segment "Open Your Heart")

Benicio del Toro

Kid Sitting on Car (segment "La Isla Bonita")

Leon

Innocent Man / Saint (segment "Like a Prayer")

Cameron Alborzian

Man (segment "Express Yourself")

Todd Gordon

Factory Worker (segment "Express Yourself")

Gustav Vintas

Prison Wardon (segment "Express Yourself")

Tony Ward

Merman (segment "Cherish")

Mark Romano

Father (segment "Oh Father")

Luis Camacho

Voguer (segment "Vogue")

Oliver Crumes Jr.

Voguer (segment "Vogue")

Donna DeLory

Voguer (segment "Vogue")

Salim Gauwloos

Voguer (segment "Vogue")

Jose Guitierez

Voguer (segment "Vogue")

Niki Haris

Voguer (segment "Vogue")

Kevin Stea

Voguer (segment "Vogue")

Gabriel Trupin

Voguer (segment "Vogue")

Carlton Wilborn

Voguer (segment "Vogue")