Alec Baldwin

Mr. Conductor

Peter Fonda

Grandpa Burnett Stone

Mara Wilson

Lily Stone

Eddie Glenn

Thomas (voice)

Neil Crone

Diesel 10 / Gordon / Splatter / Tumbleweed (voice)

Michael E. Rodgers

Mr. C. Junior

Britt Allcroft

Lady (voice)

Kevin Frank

Henry / Dodge / Bertie / Harold (voice)

Linda Ballantyne

Percy (voice)

Susan Roman

James (voice)

Colm Feore

Toby (voice)

Cody McMains

Patch

Didi Conn

Stacy Jones

Russell Means

Billy Twofeathers

Lori Hallier

Lily's Mother

Shelley-Elizabeth Skinner

Annie / Clarabel (voice)

Jared Wall

Young Bernett (voice)

Laura Bower

Young Tasha (voice)

Doug Lennox

Motorcyle Passerby (uncredited)

Mike Stoklasa

Sad Hat Man (uncredited)